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Names
X
Name
Species
Main
GTBP
False
MSH6
Homo sapiens, Mus musculus
True
Keywords
+
Location
X
Location
Species
2p16
Homo sapiens
Subcellular Localisation
X
Stage
Description
Details
Links
Protein Sequence
X
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
152.9
6.42
1360
Entrez Protein:P52701
OMIM:600678
Uniprot:P52701
1358
Uniprot:P54276
Annotation
X
Start
End
Domain
Description
90
152
PWWP
246
249
NLS
298
317
NLS BP
382
386
NLS
753
1102
MUTSd
1127
1321
MUTSac
Biological Process
X
GO ID
Term
Links
GO:0006298
mismatch repair
PubMed:10545954
OMIM:600678
pubmed:23391514
Molecular Function
X
GO ID
Term
Links
GO:0004002
ATPase activity
PubMed:10078208
GO:0003684
damaged DNA binding
PubMed:10078208
GO:0035064
methylated histone residue binding
pubmed:20850016
GO:0032301
MutSalpha complex
pubmed:23391514
Other Function
X
Function
Links
high frequency of atypical hyperplastic lesions and carcinomas of the endometrium
OMIM:600678
mutated in HNPCC
PubMed:11586295
Expression
X
Experiment
Detail
Links
Related Genes
X
Name
Species
Links
MutS
Escherichia coli
OMIM:600678
MSH6
Saccharomyces cerevisiae
OMIM:600678
MSH6
Schizosaccharomyces pombe
PubMed:11333218
msh-6
Caenorhabditis elegans
PubMed:12600937
History
X
Created On
Last Changed
2001-08-30 13:37:30
2002-06-17 11:42:16