or browse by
compartment
or
motif
About
Links
Statistics
Web Services
FAQs
Names
X
Name
Species
Main
FEN-1
Gallus gallus, Homo sapiens, Mus musculus, Rattus norvegicus
True
flap structure-specific endonuclease 1
False
MF1
False
FEN1
false
Keywords
X
base excision repair, DNA repair, endonuclease, DNA replication, okasaki fragment processing, replication fork stability, mutated in cancer, structure-specific nuclease
Location
X
Location
Species
19
Mus musculus
11q12
Homo sapiens
Subcellular Localisation
X
Stage
Description
Details
Links
Protein Sequence
X
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
42.6
8.8
380
Entrez Protein:NP_004102
PubMed:21496641
380
Uniprot:Q9JHW7
380
Uniprot:Q90YB0
378
Uniprot:P39749
Annotation
X
Start
End
Domain
Description
1
107
XPGN
29
297
53Exoc
146
218
XPGI
220
253
helix hairpin helix (HHH)
354
370
NLS BP
Biological Process
X
GO ID
Term
Links
GO:0006284
base-excision repair
PubMed:11440997
PubMed:11687589
GO:0006261
DNA-dependent DNA replication
PubMed:11258937
PubMed:14718165
PubMed:9278414
GO:0031297
replication fork processing
pubmed:24608430
GOIDHERE
DNA replication, Okazaki fragment processing
pubmed:22570407
Molecular Function
X
GO ID
Term
Links
GO:0003684
damaged DNA binding
PubMed:11258937
PubMed:14718165
GO:0003686
DNA repair enzyme
PubMed:11053418
GO:0004519
endonuclease activity
PubMed:11053418
Other Function
X
Function
Links
Expression
+
Related Genes
X
Name
Species
Links
RAD2
Schizosaccharomyces pombe
PubMed:94277093
Rad27
Saccharomyces cerevisiae
PubMed:10545607
Uniprot:P26793
History
X
Created On
Last Changed
2001-08-31 11:28:17
2002-04-16 10:32:59