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FAQs
Names
X
Name
Species
Main
ADPRT
False
PARP 1
Homo sapiens, Mus musculus
True
poly(ADP-ribose) polymerase
False
PPOL
False
PARP-1
false
ARDT1
false
PARP1
false
Keywords
+
Location
X
Location
Species
1q42
Homo sapiens
Subcellular Localisation
X
Stage
Description
Details
Links
S/G2
centromere
PubMed:10607829
metaphase - mitosis
centromere
and neocentromeres
PubMed:10607829
metaphase - mitosis
chromosomal
also on arms
PubMed:10607829
PubMed:15609038
Interphase
nucleolus
PubMed:11790298
PubMed:15615785
Interphase
repair foci
PubMed:14500814
interphase
nuclear diffuse
delocalized from nucleolus upon DNA damage
pubmed:19144573
Protein Sequence
X
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
113.1
9
1014
Entrez Protein:NP_001609
OMIM:173870
Uniprot:P09874
Annotation
+
Biological Process
X
GO ID
Term
Links
GO:0006284
base-excision repair
PubMed:10471503
PubMed:11448989
GO:0006281
DNA repair
PubMed:12866953
GO:0009048
dosage compensation, by inactivation of X chromosome
PubMed:17322296
GO:0006325
establishment and/or maintenance of chromatin architecture
PubMed:15607977
pubmed:20832725
GO:0000398
nuclear mRNA splicing, via spliceosome
PubMed:12176931
GO:0006508
proteolysis and peptidolysis
PubMed:12386937
GO:0045944
positive regulation of transcription from RNA polymerase II promoter
pubmed:19779455
pubmed:18258916
pubmed:20832725
GO:0016446
somatic hypermutation of immunoglobulin genes
pubmed:20652015
pubmed:20652015
GO:0030576
Cajal body organization
pubmed:19229318
GO:0043044
ATP-dependent chromatin remodeling
pubmed:27257257
GO:0097681
double-strand break repair via alternative nonhomologous end joining
pubmed:29929045
Molecular Function
X
GO ID
Term
Links
GO:0003686
DNA repair enzyme
PubMed:10471503
GO:0003950
NAD+ ADP-ribosyltransferase activity
PubMed:10471503
GO:0010843
promoter binding
pubmed:18258916
Other Function
X
Function
Links
Expression
X
Experiment
Detail
Links
Related Genes
X
Name
Species
Links
pme-1
Caenorhabditis elegans
PubMed:12600937
History
+