cancer, histone methylase, set domain, protein methyltransferase, zinc finger C2_H2
GO:0016571
histone methylation
GO:0006357
regulation of transcription from Pol II promoter
GO:0008276
protein methyltransferase activity
GO:0003713
transcription coactivator activity
high incidence of diffuse large B-cell lymphomas (DLBL) and a broad spectrum of unusual tumors in null mice
several missense mutations of RIZ1 in human tumor tissues and cell lines; one of these was particularly common in human DLBL tumors.