Names
X
Name
Species
Main
PRDM2 
Homo sapiens 
False 
RIZ1 
Homo sapiens, Mus musculus 
True 
Keywords
X
cancer, histone methylase, set domain, protein methyltransferase, zinc finger C2_H2
Location
+
Subcellular Localisation
X
Stage
Description
Details
Links
Protein Sequence
X
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
189 
7.02 
 
 
1719 
Entrez Protein:NP_036363
OMIM:601196
Annotation
+
Biological Process
X
GO ID
Term
Links
GO:0016571 
histone methylation 
PubMed:14633678
GO:0006357 
regulation of transcription from Pol II promoter 
PubMed:15282304
Molecular Function
X
GO ID
Term
Links
GO:0008276 
protein methyltransferase activity 
PubMed:11544182
PubMed:14633678
GO:0003713 
transcription coactivator activity 
PubMed:15282304
Other Function
X
Function
Links
high incidence of diffuse large B-cell lymphomas (DLBL) and a broad spectrum of unusual tumors in null mice 
PubMed:11544182
several missense mutations of RIZ1 in human tumor tissues and cell lines; one of these was particularly common in human DLBL tumors. 
PubMed:11544182
Expression
X
Experiment
Detail
Links
Related Genes
X
Name
Species
Links
History
X
Created On
Last Changed
2001-09-11 10:37:52 
2005-08-22 14:46:59