DNA topoisomerase II alpha
False
topoisomerase II alpha
Homo sapiens
True
ATPase, centromere protein, chromosome scaffold, chromosome segregation, meiotic chromosomes, mitotic centromere, mitotic chromosomes, nuclear mRNA splicing via spliceosome, topoisomerase, transcription elongation, replication fork reversal, stalled replication fork
prophase - meiosis
heterochromatin
centromeric heterochromatin
G2
centromere
centromeric heterochromatin concentration
metaphase - mitosis
centromere
until mid anaphase
prometapha
chromosome core
S - interphase
heterochromatin
in late S
Interphase
splicing speckles
catalytically inactive form
GO:0007002
centromere binding
GO:0007076
mitotic chromosome condensation
GO:0000398
nuclear mRNA splicing, via spliceosome
GO:0000070
mitotic sister chromatid segregation
GO:0070683
decatenation checkpoint
GO:0071932
replication fork reversal
GO:0004002
ATPase activity
GO:0003918
DNA topoisomerase (ATP-hydrolyzing) activity
Immunohistochemistry
proliferating cells
DNA topoisomerase II alpha
Gallus gallus
DNA topoisomerase II
Drosophila melanogaster
DNA topoisomerase II
Schizosaccharomyces pombe