Names
X
Name
Species
Main
TOPBP1 
Homo sapiens 
True 
Keywords
+
Location
X
Location
Species
3q22.1 
Homo sapiens 
Subcellular Localisation
X
Stage
Description
Details
Links
S - interphase 
BRCA1 nuclear dots 
brca1 foci 
PubMed:11395493
S - interphase 
replication foci 
with brca1 after inhibition of replication 
PubMed:11395493
Interphase 
PML/ND10 bodies 
 
PubMed:12773567
meiosis 
chromosomal 
 
PubMed:14718568
Mitosis 
centrosome 
 
pubmed:21291884
Protein Sequence
X
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
160.6 
6.5 
 
 
1435 
Entrez Protein:NP_008958
genelynxhs:8598
Uniprot:Q9UEB9
Annotation
+
Biological Process
X
GO ID
Term
Links
GO:0006281 
DNA repair 
PubMed:11395493
PubMed:16530042
pubmed:18519640
pubmed:19289795
pubmed:19289795
GO:0007095 
mitotic G2 checkpoint 
PubMed:12810625
GO:0006357 
regulation of transcription from Pol II promoter 
PubMed:15075294
pubmed:17913746
GO:0006270 
DNA replication initiation 
pubmed:20116089
pubmed:20159562
GO:0006270 
DNA replication initiation 
GO:0000076 
DNA replication checkpoint 
pubmed:21482717
GO:0000076 
DNA replication checkpoint 
pubmed:21482717
GO:0022008 
neurogenesis 
pubmed:22522401
GOIDHERE 
genome stability 
pubmed: 25762097
pubmed:25794620
GO:0007128 
meiotic prophase I 
pubmed:29114052
Molecular Function
X
GO ID
Term
Links
GO:0003684 
damaged DNA binding 
PubMed:10498869
Other Function
X
Function
Links
Expression
X
Experiment
Detail
Links
Related Genes
X
Name
Species
Links
Dpb11 
Saccharomyces cerevisiae 
PubMed:11395493
pubmed:16840526
cut5 
Schizosaccharomyces pombe 
PubMed:11395493
Mus101 
Drosophila melanogaster 
PubMed:11014818
History
+