Names
Name
Species
Main
AIK2 
 
False 
AIM-1 
 
False 
AIR_2 
Caenorhabditis elegans 
False 
AIRK2 
 
False 
Aurora 1 
 
False 
Aurora B 
Homo sapiens 
True 
STK12 
 
False 
Keywords
C.elegans, chromosomal passenger, chromosome scaffold, cytokinesis, expression peaks at the G2M transition, histone phosphorylation, human, kinase, kinase activity is maximal during mitosis, mass spectrometry, meiotic chromosomes, mitotic centromere, mitotic chromosomes, serine threonine kinase, spindle assembly
Location
Location
Species
11 
Mus musculus 
17p13.1 
Homo sapiens 
Subcellular Localisation
Stage
Description
Details
Links
metaphase - mitosis 
centromere 
+ inactive cen 
telophase 
cleavage furrow 
 
G2 
chromatin 
with phosphoH3 
telophase 
cleavage midbody 
 
meiosis I 
chromosomal 
localized to the region of the bivalents where sister chromatid cohesion is lost 
Protein Sequence
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
Annotation
Start
End
Domain
Description
77 
327 
S_TKc 
 
226 
232 
NLS 
 
Biological Process
GO ID
Term
Links
GO:0007076 
mitotic chromosome condensation 
GO:0007094 
mitotic spindle checkpoint 
GO:0045143 
homologous chromosome segregation 
GO:0000070 
mitotic sister chromatid segregation 
GO:0007063 
regulation of sister chromatid cohesion 
Molecular Function
GO ID
Term
Links
GO:0004674 
protein serine/threonine kinase activity 
Other Function
Function
Links
Expression
Experiment
Detail
Links
Related Genes
Name
Species
Links
Ipl1 
Saccharomyces cerevisiae 
AIR2 
Caenorhabditis elegans 
ark1 
Schizosaccharomyces pombe 
History
Created On
Last Changed
2001-10-05 17:31:46 
2007-06-11 11:48:30