histone deacetylase complex, human, myogenesis, transcription corepressor
Interphase
nuclear-cytoplasmic shuttling
P leads to binding to 14-3-3 and nuclear export
GO:0000122
negative regulation of transcription from Pol II promoter
inhibitor of myogenesis. Ser phosphorylation by myogenic factors stimulates binding to 14-3-3 and disrupts MEF2 interaction. Moved out of nucleus
2001-11-15 15:22:42
2002-04-15 09:49:37