DIHYDROTESTOSTERONE RECEPTOR
False
endocrine receptor, genetic disease, homodimer, ligand binding domain holi, nuclear receptor, zinc finger C4
Interphase
nuclear
upon androgen exposure
Interphase
cytoplasmic
in absence of ligand
S - interphase
replication foci
GO:0006357
regulation of transcription from Pol II promoter
GO:0003706
ligand-regulated transcription factor activity
ARKO male mice have a female-like appearance and body weight. Spermatogenesis is arrested at pachytene spermatocytes. Potential defects in female fertility and/or ovulation
Required in Sertoli cells. Conditional ko
2001-12-04 16:05:50
2004-08-16 12:13:19