Names
X
Name
Species
Main
DAP80b 
 
False 
FUS 
 
False 
POMp75 
 
False 
TLS 
Homo sapiens 
True 
Keywords
X
genetic disease, ActD movement, cancer, RRM, miRNA processing, nuclear foci, nuclear mRNA splicing via spliceosome, prespliceosome, zinc finger RBZ, translation regulation, cytoplasmic stress granules, RGG, phase separation, prion-like domain, poly ADP ribose binding
Location
X
Location
Species
16p11.2 
Homo sapiens 
Subcellular Localisation
X
Stage
Description
Details
Links
Interphase 
nuclear dots 
TLS-CHOP fusion protein localises to nuclear bodies - not PML 
PubMed:11802205
actinomycin D 
nucleolus 
 
PubMed:9053842
Interphase 
cytoplasmic 
after DNA damage 
pubmed:24899704
pubmed:24842888
Interphase 
cytoplasmic stress granules 
 
pubmed:24297750
Interphase 
repair foci 
after DNA damage 
pubmed:26317470
Protein Sequence
X
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
53.4 
9.4 
 
 
526 
Entrez Protein:NP_004951
PubMed:20668259
OMIM:137070
Uniprot:P35637
PubMed: 24509083
Annotation
X
Start
End
Domain
Description
286 
367 
RRM 
 
424 
450 
ZnF RBZ 
 
Biological Process
X
GO ID
Term
Links
GO:0030918 
microRNA processing 
PubMed:15531877
GO:0000398 
nuclear mRNA splicing, via spliceosome 
PubMed:10779324
PubMed:12176931
PubMed:12477934
GO:0006417 
regulation of translation 
pubmed:24297750
Molecular Function
X
GO ID
Term
Links
GO:0003723 
RNA binding 
PubMed:8187069
PubMed:9264461
GOIDHERE 
poly(ADP-ribose) binding 
pubmed:26317470
Other Function
X
Function
Links
lymphocyte development and chromosome instability 
PubMed: 10655065
Expression
X
Experiment
Detail
Links
Related Genes
X
Name
Species
Links
History
X
Created On
Last Changed
2002-01-23 16:17:34 
2005-02-16 14:23:42