Names
Name
Species
Main
YT521 
 
false 
AK056430 
Homo sapiens 
False 
GH01918 
Drosophila melanogaster 
False 
KIAA1966 
Homo sapiens 
False 
YT521-B 
Homo sapiens 
True 
YTHDC1 
 
false 
Keywords
ActD movement, mRNA splicing, YTH domain, methylated RNA binding, RNA binding, sam68 nuclear body, YT bodies, m6A RNA binding, XIST RNA binding
Location
Location
Species
4q13.2 
Homo sapiens 
Subcellular Localisation
Stage
Description
Details
Links
Interphase 
Sam68 bodies 
Colocalises with Sam68 in 5-20 bodies/cell, also interacts with SAF-B and p59(fyn) disrupts local. 
S/G2 
Sam68 bodies 
First appear in S phase seen adjacent to splicing speckles and coiled bodies 
Mitosis 
 
Disperse at mitosis 
actinomycin D 
nuclear diffuse 
Act. D treatment NOT dispersed by a-a-aminitin or DRB 
Protein Sequence
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
Annotation
Start
End
Domain
Description
193 
265 
coiled-coil 
 
354 
495 
YTH 
 
Biological Process
GO ID
Term
Links
GO:0006364 
rRNA processing 
GOIDHERE 
regulation of mRNA splicing, via spliceosome 
GO:0009048 
dosage compensation by inactivation of X chromosome 
Molecular Function
GO ID
Term
Links
GO:0008248 
pre-mRNA splicing factor activity 
GO:0003723 
RNA binding 
GO:1990247 
N6-methyladenosine-containing RNA binding 
Other Function
Function
Links
Expression
Experiment
Detail
Links
Northern 
Ubiquitous 
In situ 
neurons, cell type specific in the brain 
Related Genes
Name
Species
Links
AAH22697 
Mus musculus 
AK056430 
Homo sapiens 
GH01918 
Drosophila melanogaster 
History
Created On
Last Changed
2002-03-12 12:55:19 
2005-02-16 14:30:58