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Names
X
Name
Species
Main
FACE1
False
ZINC METALLOPROTEINASE STE24
False
ZMPSTE24
Homo sapiens, Mus musculus
True
CAAX prenyl protease 1 homolog
false
MADB
false
Keywords
X
dilated cardiomyopathy muscular dystrophy and lipodystrophy, genetic disease, house mouse, human, metallopeptidase, peptidase, protease
Location
X
Location
Species
1p34
Homo sapiens
4
Mus musculus
Subcellular Localisation
X
Stage
Description
Details
Links
Interphase
endoplasmic reticulum
PubMed:11923874
Interphase
nuclear periphery
PubMed:11923874
Protein Sequence
X
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
54.8
7.11
475
Entrez Protein:NP_005848
PubMed:15317753
PubMed:15843403
OMIM:606480
Uniprot:O75844
54.6
475
Entrez Protein:NP_766288
Annotation
X
Start
End
Domain
Description
20
37
transmembrane
80
102
transmembrane
122
144
transmembrane
171
193
transmembrane
197
219
transmembrane
237
469
peptidase M48
389
411
transmembrane
Biological Process
X
GO ID
Term
Links
GO:0006997
nuclear organization and biogenesis
PubMed:11923874
PubMed:12913070
PubMed:15317753
PubMed:15671064
Molecular Function
X
GO ID
Term
Links
GO:0008487
prenyl-dependent CAAX protease activity
PubMed:11923874
PubMed:mandibuloacral dyspl
Other Function
X
Function
Links
dilated cardiomyopathy, muscular dystrophy and lipodystrophy
PubMed:11923874
Expression
X
Experiment
Detail
Links
Northern
Ubiquitous
Related Genes
X
Name
Species
Links
Ste24
Saccharomyces cerevisiae
Afc1
Saccharomyces cerevisiae
History
X
Created On
Last Changed
2002-04-02 11:38:57
2002-04-02 11:57:24