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Names
X
Name
Species
Main
DIGEORGE CRITICAL REGION GENE 1; DGCR1
Homo sapiens
False
HIRA
Mus musculus
True
TUP1 like enhancer of split protein 1
Homo sapiens, Mus musculus
False
TUPLE1
Mus musculus
False
Keywords
+
Location
X
Location
Species
22q11
Homo sapiens
MMU16
Mus musculus
Subcellular Localisation
X
Stage
Description
Details
Links
Interphase
nuclear
putative localisation, no IF data
PubMed:9063745
PubMed:8611624
senescence
PML/ND10 bodies
as cells approach senescence
PubMed:15621527
pubmed: 21347226
Interphase
ALT-associated PML body
pubmed: 21347226
Protein Sequence
X
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
111.62
8.37
1015
PubMed:16980972
Entrez Protein:CAA63334
Uniprot:Q61666
1017
OMIM:600237
Entrez Protein:NP_003316
Uniprot:P54198
Annotation
X
Start
End
Domain
Description
68
98
WD40
WD1 domain, G-beta repeat
129
159
WD40
WD2
172
202
WD40
WD3
206
313
WD40
WD4
267
286
NLS
(putative)
408
418
Poly_Gln
poly glutamine region
626
643
NLS
(putative)
638
641
Poly_Lys
poly lysine region
803
806
Poly_Val
poly valine region
Biological Process
X
GO ID
Term
Links
GO:0006336
DNA replication-independent nucleosome assembly
PubMed:14718166
GO:0006325
establishment and/or maintenance of chromatin architecture
PubMed:15621527
GO:0006357
regulation of transcription from Pol II promoter
PubMed:9063745
GO:0006338
chromatin remodeling
pubmed:18354397
Molecular Function
X
GO ID
Term
Links
GO:0003677
DNA binding
PubMed:9063745
GO:0003702
RNA polymerase II transcription factor activity
PubMed:9063745
Other Function
X
Function
Links
Gastrulation Defects and Patterning Abnormalities of Mesoendodermal Derivatives
PubMed Central:11884616
Expression
+
Related Genes
X
Name
Species
Links
Hir1p
Saccharomyces cerevisiae
PubMed:8417331
Hir2p
Saccharomyces cerevisiae
PubMed:8417331
CAF-I p60
Homo sapiens
PubMed:7600578
History
X
Created On
Last Changed
2002-04-06 09:59:55
2005-03-24 11:23:32