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Names
X
Name
Species
Main
LEF_1
Homo sapiens, Mus musculus, Rattus norvegicus
True
TCF1-alpha
False
Keywords
X
hmg box, sumoylated, nuclear foci
Location
X
Location
Species
4q23-q25
Homo sapiens
3
Mus musculus
Subcellular Localisation
X
Stage
Description
Details
Links
Interphase
when sumoylated by PIAS
nuclear foci
pubmed:11731474
Protein Sequence
X
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
44.2
6.9
399
Entrez Protein:NP_057353
OMIM:153245
Uniprot:Q9UJU2
397
Entrez Protein:P27782
Uniprot:P27782
397
Uniprot:Q9QXN1
Annotation
X
Start
End
Domain
Description
298
368
HMG box
374
380
NLS
1
213
CTNNB1_binding
Biological Process
X
GO ID
Term
Links
Molecular Function
X
GO ID
Term
Links
GO:0003677
DNA binding
PubMed:7651541
Other Function
X
Function
Links
Postnatal lethality.Lacked teeth, mammary glands, whiskers, and hair. Lack neural crest-derived neuronal populations. No defects in lymphoid cell populations.
PubMed:7537238
Expression
X
Experiment
Detail
Links
Related Genes
X
Name
Species
Links
History
+