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Names
X
Name
Species
Main
SOX2
Gallus gallus, Homo sapiens, Mus musculus
True
Keywords
X
neuronal differentiation, genetic disease, enhancer binding, pluripotency, stem cell, hmg box, trophectoderm, pioneer factor
Location
+
Subcellular Localisation
X
Stage
Description
Details
Links
Protein Sequence
X
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
34.3
9.74
317
Entrez Protein:P48431
PubMed:16543359
OMIM:184429
Uniprot:P48431
319
Entrez Protein:P48432
Uniprot:P48432
315
Entrez Protein:P48430
Uniprot:P48430
Annotation
X
Start
End
Domain
Description
38
59
NLS BP
40
110
HMG box
111
118
NLS
Biological Process
X
GO ID
Term
Links
GO:0009790
embryonic development
PubMed:12514105
PubMed:17515932
GO:0006357
regulation of transcription from Pol II promoter
PubMed:12167158
GO:0001829
trophectodermal cell differentiation
pubmed:21103067
Molecular Function
X
GO ID
Term
Links
GO:0008301
DNA bending activity
PubMed:11584012
GO:0003677
DNA binding
PubMed:11358870
PubMed:12167158
PubMed:17097055
GO:0003704
specific RNA polymerase II transcription factor activity
PubMed:12167158
GOIDHERE
RNA polymerase II transcription factor activity, enhancer binding
pubmed:20621055
Other Function
X
Function
Links
lens induction
PubMed:12612584
Expression
X
Experiment
Detail
Links
In situ
expressed in the epiblast and extraembryonic ectoderm of the egg cylinder, becoming restricted to the prospective neural plate and chorion at the onset of gastrulation.
PubMed:10446282
pubmed:21663792
neural precursors
pubmed: 22085726
pubmed:21663792
Related Genes
X
Name
Species
Links
History
X
Created On
Last Changed
2002-11-14 11:04:07
2006-05-29 16:37:20