Names
X
Name
Species
Main
ALR 
Homo sapiens 
True 
ARL-1 
 
False 
MLL4 
 
False 
KMT2D 
 
false 
KABUK1 
 
false 
MLL2 
 
false 
Keywords
X
histone methylation, hmg box, set domain, fycn, PHD finger, spermatogenesis, genetic disease, H3K4 methylation, MLL1/2 complex, lymphoma, Kabuki syndrome, congenital heart disease, FY-rich domain, H4K16ac binding
Location
+
Subcellular Localisation
X
Stage
Description
Details
Links
Protein Sequence
X
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
564.2 
5.65 
 
 
5262 
Entrez Protein:NP_003473
OMIM:602113
Uniprot:O14686
PubMed:20711175
PubMed: 21796119
OMIM:147920
PubMed:23665959
Annotation
+
Biological Process
X
GO ID
Term
Links
GO:0030154 
cell differentiation 
PubMed:17429066
GO:0016571 
histone methylation 
pubmed:19348672
pubmed:20808952
pubmed:23934151
pubmed:24423662
pubmed:26932671
GO:0000122 
negative regulation of transcription from RNA polymerase II promoter 
pubmed:19348672
pubmed:20808952
GO:0007283 
spermatogenesis 
pubmed:19348672
GO:0060260 
regulation of transcription initiation from RNA polymerase II promoter 
pubmed:19703992
GO:0048477 
oogenesis 
pubmed:20808952
GO:0007611 
learning or memory 
pubmed: 23426673
GO:0048864 
stem cell development 
pubmed:23934151
GOIDHERE 
craniofacial development 
pubmed:25972376
GO:0007507 
heart development 
pubmed:25972376
pubmed:26932671
GO:0007420 
brain development 
pubmed:25972376
Molecular Function
X
GO ID
Term
Links
GO:0042800 
histone methyltransferase activity (H3-K4 specific) 
pubmed:19348672
pubmed:23934151
pubmed:24423662
pubmed:26932671
GO:0070577 
lysine-acetylated histone binding 
pubmed:31127101
Other Function
X
Function
Links
Expression
X
Experiment
Detail
Links
Related Genes
X
Name
Species
Links
trithorax 
Drosophila melanogaster 
PubMed:12151224
Set1 
Saccharomyces cerevisiae 
PubMed:12151224
History
X
Created On
Last Changed
2002-11-14 14:51:50 
2007-09-25 13:23:30