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Names
X
Name
Species
Main
HES1
Gallus gallus, Homo sapiens, Mus musculus, Rattus norvegicus
True
HHL
False
HRY
False
Keywords
X
differentiation, HLH, oscillatory, transcription repression
Location
+
Subcellular Localisation
X
Stage
Description
Details
Links
Protein Sequence
X
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
29.5
9.66
280
Entrez Protein:NP_005515
OMIM:139605
Uniprot:Q14469
282
Entrez Protein:P35428
Uniprot:P35428
281
Entrez Protein:Q04666
Uniprot:Q04666
290
Entrez Protein:O57337
Uniprot:O57337
Annotation
X
Start
End
Domain
Description
40
47
NLS
40
97
HLH
108
152
orange
Biological Process
X
GO ID
Term
Links
GO:0000122
negative regulation of transcription from Pol II promoter
PubMed:11038350
pubmed:20832754
GO:0048863
stem cell differentiation
pubmed:20545770
pubmed:19684110
GO:0045746
negative regulation of Notch signaling pathway
pubmed:20545770
Molecular Function
X
GO ID
Term
Links
GO:0003677
DNA binding
PubMed:11038350
Other Function
X
Function
Links
Expression
X
Experiment
Detail
Links
oscillates in ES cells
pubmed:20545770
oscillates in presomitic mesoderm
pubmed:10704388
Related Genes
X
Name
Species
Links
hairy
Drosophila melanogaster
History
X
Created On
Last Changed
2003-01-23 13:52:34
2003-01-23 14:03:31