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Names
X
Name
Species
Main
DCLRE1A
Homo sapiens
False
KIAA0086
Homo sapiens
False
Snm1
Homo sapiens, Mus musculus
True
Snm1a
False
Keywords
X
interstrand crosslinks, ubiquitin binding, DNA damage, DNA repair, BRCA1 nuclear dots, checkpoint, nuclease
Location
+
Subcellular Localisation
X
Stage
Description
Details
Links
Interphase
nuclear speckles
snm1 bodies
PubMed:12446782
PubMed:15572677
Interphase
BRCA1 nuclear dots
foci increase after dna damage. Colocalises with mre11
PubMed:12446782
Protein Sequence
X
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
116.4
8.24
1040
Entrez Protein:NP_055696
Uniprot:Q6PJP8
1023
Entrez Protein:NP_061301
Annotation
X
Start
End
Domain
Description
16
21
NLS
345
348
NLS
566
573
NLS
685
701
NLS BP
991
1017
DRMBL
Biological Process
X
GO ID
Term
Links
GO:0006281
DNA repair
PubMed:12446782
pubmed:15572677
GO:0000077
DNA damage checkpoint
pubmed: 18848520
GO:0036297
interstrand cross-link repair
pubmed:21896658
pubmed:20385554
Molecular Function
X
GO ID
Term
Links
GOIDHERE
5.-3. exonuclease activity
pubmed:20175117
pubmed:22692201
GO:0043130
ubiquitin binding
pubmed:20385554
Other Function
X
Function
Links
Expression
X
Experiment
Detail
Links
Related Genes
X
Name
Species
Links
Snm1
Saccharomyces cerevisiae
Entrez Protein:S19646
pso2
Schizosaccharomyces pombe
pubmed:20175117
History
X
Created On
Last Changed
2003-01-24 15:54:03
2006-06-22 16:02:09