Names
X
Name
Species
Main
AN34 
 
False 
AP endonuclease 1 
 
False 
Ape1 
Homo sapiens 
True 
apen 
 
False 
apex nuclease 
 
False 
apex1 
 
False 
HAP1 
 
False 
REF-1 
 
False 
Keywords
X
acetylated, base excision repair, endonuclease, exonuclease, human, nucleotide excision repair, transcription repression
Location
X
Location
Species
14q12 
Homo sapiens 
Subcellular Localisation
X
Stage
Description
Details
Links
Protein Sequence
X
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
35.6 
8.33 
 
 
318 
Entrez Protein:P27695
genelynxhs:ENSP00000216714
OMIM:107748
Uniprot:P27695
Annotation
X
Start
End
Domain
Description
2 
8 
NLS 
 
21 
27 
NLS 
 
62 
316 
Exo_endo_phos 
 
Biological Process
X
GO ID
Term
Links
GO:0006284 
base-excision repair 
PubMed:14973123
pubmed:29486702
GO:0006281 
DNA repair 
PubMed:11832948
GO:0000122 
negative regulation of transcription from Pol II promoter 
PubMed:14633989
GO:0006289 
nucleotide-excision repair 
PubMed:14704345
GO:0006309 
DNA fragmentation during apoptosis 
PubMed:12842873
Molecular Function
X
GO ID
Term
Links
GO:0008408 
3.-5. exonuclease activity 
PubMed:11832948
GO:0003677 
DNA binding 
PubMed:14633989
GO:0003686 
DNA repair enzyme 
PubMed:11832948
GO:0004519 
endonuclease activity 
PubMed:12842873
Other Function
X
Function
Links
essential for early embryonic development 
PubMed:8799128
Expression
X
Experiment
Detail
Links
Related Genes
X
Name
Species
Links
History
X
Created On
Last Changed
2003-07-07 14:16:05 
2004-08-26 12:58:07