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Names
X
Name
Species
Main
E2F-1
False
E2F1
Homo sapiens, Mus musculus
True
PBR3
False
RBAP-1
False
RBBP3
False
Keywords
X
8653789, E2F, heterodimer, homodimer, house mouse, human, transcription factor, tumour suppressor
Location
+
Subcellular Localisation
X
Stage
Description
Details
Links
Protein Sequence
X
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
46.9
4.79
437
Entrez Protein:Q01094
OMIM:189971
Uniprot:Q01094
430
Entrez Protein:Q61501
Uniprot:Q61501
Annotation
X
Start
End
Domain
Description
1
31
signal peptide
86
93
NLS
123
338
E2F_TDP
Biological Process
X
GO ID
Term
Links
GO:0006915
apoptosis
PubMed:11034215
GO:0000122
negative regulation of transcription from Pol II promoter
PubMed:10199402
GO:0000080
G1 phase of mitotic cell cycle
PubMed:10199402
GO:0006357
regulation of transcription from Pol II promoter
PubMed:8618861
Molecular Function
X
GO ID
Term
Links
GO:0003677
DNA binding
PubMed:1638634
PubMed:7784053
GO:0008181
tumor suppressor
PubMed: 8653789
Other Function
X
Function
Links
skeletal muscle regeneration
PubMed:15304485
Expression
+
Related Genes
X
Name
Species
Links
History
X
Created On
Last Changed
2004-02-24 13:27:31
2004-09-29 11:39:26