Names
Name
Species
Main
ASXL1 
Homo sapiens 
True 
KIAA0978 
 
false 
Additional sex combs-like 1 
 
false 
Keywords
myeloid leukaemia, AML, LXXLL, homeotic gene regulation, haemopoiesis, genetic disease, PHD finger, mutated in cancer, nuclear receptor interacting, Bohring-Opitz syndrome, histone deubiquitination
Location
Location
Species
20q11.1 
 
Subcellular Localisation
Stage
Description
Details
Links
Annotation
Start
End
Domain
Description
284 
288 
LXXLL 
 
Biological Process
GO ID
Term
Links
GO:0045888 
regulation of transcription of homeotic gene (Polycomb group) 
GO:0045890 
regulation of transcription of homeotic gene (trithorax group) 
GO:0000122 
negative regulation of transcription from RNA polymerase II promoter 
GO:0072500 
negative regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor 
GO:0061484 
hematopoietic stem cell homeostasis 
GO:1903584 
regulation of histone deubiquitination 
Molecular Function
GO ID
Term
Links
GO:0030374 
ligand-dependent nuclear receptor transcription coactivator activity 
Other Function
Function
Links
mutated in CML and myelodysplasia 
Expression
Related Genes
Name
Species
Links
Asx 
Drosophila melanogaster 
History
Created On
Last Changed
2009-10-29 17:16:41 
0000-00-00 00:00:00