E3 ligase, histone ubiquitination, apoptosis, dna damage response, uba, WWE domain, hect domain, intellectual disability, ds break repair
GO:0006915
apoptotic process
GO:0034984
cellular response to DNA damage stimulus
GO:0006302
double-strand break repair
GO:0061630
ubiquitin protein ligase activity
GO:0016574
histone ubiquitination