Names
X
Name
Species
Main
p53 
Homo sapiens 
True 
TP53 
 
False 
LFS1 
 
false 
Keywords
+
Location
X
Location
Species
17p13.1 
Mus musculus 
Subcellular Localisation
X
Stage
Description
Details
Links
Interphase 
nuclear-cytoplasmic shuttling 
shuttles. Accumulates in nucleus after stress. Monoubiquitination leads to nuclear export. 
PubMed:11329373
Interphase 
nucleolar 
In cells treated with MG132 and in nucleolar cavities 
PubMed:11329373
pubmed: 20332106
pubmed:25723258
Interphase 
Cajal bodies 
 
PubMed:11704667
Interphase 
PML/ND10 bodies 
interaction with HIPK2 
PubMed:11740489
Interphase 
IR-induced foci 
with gamma H2A.X and ATM 
PubMed:16322227
Protein Sequence
X
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
43.7 
6.48 
53 
 
393 
OMIM:151623
OMIM:191170
Entrez Protein:NP_000537
Uniprot:P04637
Annotation
+
Biological Process
X
GO ID
Term
Links
GO:0006915 
apoptosis 
PubMed:9305847
GO:0006338 
chromatin remodeling 
PubMed:12574133
GO:0000122 
negative regulation of transcription from Pol II promoter 
PubMed:15531928
GO:0006289 
nucleotide-excision repair 
PubMed:12574133
GO:0006974 
response to DNA damage stimulus 
GO:0006357 
regulation of transcription from Pol II promoter 
PubMed:8414502
GO:0031937 
positive regulation of chromatin silencing 
pubmed: 33060137
Molecular Function
X
GO ID
Term
Links
GO:0003682 
chromatin binding 
PubMed:11511360
GO:0003677 
DNA binding 
PubMed: 8276238
PubMed:11511360
PubMed:8414502
GO:0000981 
sequence-specific DNA binding RNA polymerase II transcription factor activity 
pubmed:25391375
Other Function
X
Function
Links
Expression
X
Experiment
Detail
Links
Related Genes
X
Name
Species
Links
History
X
Created On
Last Changed
2001-05-02 10:05:00 
2006-01-31 16:50:19