Names
Name
Species
Main
ASXL1 
Homo sapiens 
True 
KIAA0978 
 
false 
Additional sex combs-like 1 
 
false 
Keywords
myeloid leukaemia, AML, LXXLL, homeotic gene regulation, haemopoiesis, genetic disease, PHD finger, mutated in cancer, nuclear receptor interacting, Bohring-Opitz syndrome, histone deubiquitination
Location
Location
Species
20q11.1 
 
Subcellular Localisation
Stage
Description
Details
Links
Annotation
Start
End
Domain
Description
284 
288 
LXXLL 
 
Biological Process
GO ID
Term
Links
GO:0045888 
regulation of transcription of homeotic gene (Polycomb group) 
GO:0045890 
regulation of transcription of homeotic gene (trithorax group) 
GO:0000122 
negative regulation of transcription from RNA polymerase II promoter 
GO:0072500 
negative regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor 
GO:0061484 
hematopoietic stem cell homeostasis 
GO:1903584 
regulation of histone deubiquitination 
Molecular Function
GO ID
Term
Links
GO:0030374 
ligand-dependent nuclear receptor transcription coactivator activity 
Other Function
Function
Links
mutated in CML and myelodysplasia 
Expression
Experiment
Detail
Links
Related Genes
Name
Species
Links
Asx 
Drosophila melanogaster 
History
Created On
Last Changed
2009-10-29 17:16:41 
0000-00-00 00:00:00