Names
X
Name
Species
Main
53BP1 
Homo sapiens 
True 
TP53BP1 
 
false 
p202 
 
false 
Keywords
+
Location
X
Location
Species
15q15-q21 
Homo sapiens 
Subcellular Localisation
X
Stage
Description
Details
Links
Interphase 
nuclear diffuse 
 
Interphase 
IR-induced foci 
after irradiation to induce ds breaks. Co-localisation to mre11/rad50 foci. Requires H2A.X 
PubMed:11134068
PubMed:12447390
PubMed:15840649
prophase - mitosis 
kinetochore 
co-localisation with CENP-E 
PubMed:11801725
metaphase - mitosis 
kinetochore 
released by mid anaphase 
PubMed:11801725
Interphase 
repair foci 
 
pubmed: 21317883
Interphase 
OPT domain 
 
pubmed:21444690
Protein Sequence
X
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
214 
4.62 
 
 
1977 
Entrez Protein:NP_001135452
Uniprot:Q12888
Annotation
+
Biological Process
X
GO ID
Term
Links
GO:0006281 
DNA repair 
PubMed:11134068
PubMed:17190600
GO:0006357 
regulation of transcription from Pol II promoter 
PubMed:11134068
GO:0016447 
somatic recombination of antibody genes 
PubMed:15159415
pubmed:21549309
pubmed:23760478
GO:0006303 
double-strand break repair via nonhomologous end joining 
pubmed: 23377543
pubmed:18158901
pubmed:18931659
pubmed:29160738
GO:0072421 
detection of DNA damage stimulus involved in DNA damage checkpoint 
pubmed:20871591
GO:2001034 
positive regulation of double-strand break repair via nonhomologous end joining 
pubmed:29160738
pubmed:28564601
GOIDHERE 
mitosis 
pubmed:27432897
Molecular Function
X
GO ID
Term
Links
GO:0003682 
chromatin binding 
PubMed:15525939
PubMed:17190600
GO:0035064 
methylated histone residue binding 
pubmed:18158901
pubmed:28564601
GO:0061649 
ubiquitinated histone binding 
pubmed:23760478
Other Function
X
Function
Links
Expression
X
Experiment
Detail
Links
Related Genes
X
Name
Species
Links
Rad9 
Saccharomyces cerevisiae 
crb2 
Schizosaccharomyces pombe 
History
X
Created On
Last Changed
2001-10-12 17:14:47 
2005-04-26 13:48:40